With some great support from a busy medical team at Parc y Scarlets this week and a typically large dose of West Wales guts and resolve, the Scarlets field a side with only two changes to the starting line-up from last weekend.
The Scarlets' equal top try scorer this season Andy Fenby returns to the starting line-up on the wing after recovering from a dead leg injury with Gareth Maule in centre partnership with Scott Williams to replace the injured Jon Davies (groin).
Scarlets Head Coach Simon Easterby makes no changes up front - backing the same pack that delivered a strong, brave and committed first 40 minutes that gave the Scarlets had a upper hand against a formidable French side last weekend.
New second row signing Argentinean international Tomás Vallejos comes onto the bench with the opportunity to earn his first appearance in a Scarlets jersey and first experience in the Heineken Cup. Second row Sione Timani is ruled out with a minor knee injury.
Morgan Stoddart is free to play after a double yellow carding last weekend and is on the bench for Saturday afternoon's big contest.
Head Coach Simon Easterby said the Scarlets were eager for their second European contest against Heineken holders Leinster after disappointment in France, and they look forward to the challenge and intensity of playing Heineken rugby on home soil this weekend.
Easterby added that while the Scarlets took first blood in the first of their four encounters with Leinster this season, the battle on Saturday would be a huge step-up from last time out.
He said: "We can't read too much into our first result, we know that Leinster will come here with a renewed intensity and ambition not least because it's Heineken Cup second round but they are the holders of the European Cup and showed last week against Exeter that they won't give up that crown without a fight."
"Our games against Leinster are always highly competitive and tightly fought contests and we know that after our fortunes in France last week, we need to get a result here this afternoon to maintain a grip on our European campaign.
"The boys have had an excellent attitude this week. After the bitter frustration last weekend in France and a lot of tired and bruised bodies - the work ethic in training, coupled with the effort and commitment they've shown from Monday morning to pick themselves up and re-focus on this huge game as been significant.
"With four players making their Heineken Cup debuts last weekend, Samson Lee, George Earle, Joe Snyman and Richard Kelly there was no lack of edge, spirit, courage or determination from the boys and we can take confidence from our opening 40 minutes."
"This is a must win game for us but one that is still firmly in our grasp. I have no doubt it will be another great Scarlets European occasion and we'll be delighted to welcome crowds of supporters from across our region."
Scarlets team v Leinster Saturday 20th October 2012, Parc y Scarlets kick-off 1.35pm:
15 Liam Williams
14 George North
13 Gareth Maule
12 Scott Williams
11 Andy Fenby
10 Rhys Priestland
9 Tavis Knoyle
1 Phil John
2 Matthew Rees
3 Samson Lee
4 George Earle
5 Johan Snyman
6 Aaron Shingler
7 Josh Turnbull
8 Rob McCusker (capt)
Replacements: 16 Ken Owens, 17 Shaun Hopkins, 18 Deacon Manu, 19 Tomás Vallejos, 20 Johnathan Edwards, 21 Gareth Davies, 22 Aled Thomas, 23 Morgan Stoddart
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The Scarlets will host a Pembrokeshire and Ceredigion day for their big Heineken Cup occasion on Saturday afternoon. To celebrate the Scarlets' close links with their communities in West Wales, the Scarlets have invited clubs, schools and businesses from their West Wales counties to enjoy the best of European rugby at heart and soul rugby country.
Free buses and group discount tickets have been offered as part of the Heineken celebration with special guests from Aberystwyth University and Aberystwyth Rugby Club as well as Pembroke Rugby Club, Neyland, Whitland and Haverfordwest Rugby Clubs.
The Scarlets have sold out hospitality for their big European Saturday with more than 1,000 corporate hospitality rugby guests being entertained at Parc y Scarlets this weekend.